Pulse Brain · Growing Health Evidence Index
Peer-reviewed

The mechanical characterization of blood vessels and their substitutes in the continuous quest for physiological-relevant performances. A critical review

Dimitria Bonizol Camasão, Diego Mantovani

Materials Today Bio · 2021

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Summary

During the last 50 years, novel biomaterials and tissue engineering techniques have been investigated to produce alternative vascular substitutes that recapitulate the unique elastic mechanical features of blood vessels. A large variation in mechanical characterization, including the test type, protocol, and data analysis, is present in literature which complicates the comparison among studies and prevents the blooming and the advancement of this field. In addition, a limited mechanical assessment of the substitute for the intended application is often provided. In this light, this review presents the mechanical environment of blood vessels, discusses their mechanical behavior responsible for the suited blood flow into the body (non-linearity, anisotropy, hysteresis, and compliance), and c

Source type
Peer-reviewed study
DOI
10.1016/j.mtbio.2021.100106
Catalogue ID
SNmojbimf5-zg9bc8
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