Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation: Outcomes at 2 Years

Bernard Iung, Xavier Armoiry, Alec Vahanian, Florent Boutitie, Nathan Mewton, Jean‐Noël Trochu, Thierry Lefèvre, David Messika‐Zeitoun, Patrice Guérin, Bertrand Cormier, Éric Brochet, Hélène Thibault, Dominique Himbert, Sophie Thivolet, Guillaume Leurent, Guillaume Bonnet, Erwan Donal, Nicolas Piriou, Christophe Piot, Gilbert Habib, Frédéric Rouleau, Didier Carrié, Mohammed Nejjari, Patrick Ohlmann, Christophe Saint Etienne, Lionel Leroux, Martine Gilard, Géraldine Samson, Gilles Rioufol, Delphine Maucort‐Boulch, Jean François Obadia

European Journal of Heart Failure · 2019

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Summary

AIMS: The MITRA-FR trial showed that among symptomatic patients with severe secondary mitral regurgitation, percutaneous repair did not reduce the risk of death or hospitalization for heart failure at 12 months compared with guideline-directed medical treatment alone. We report the 24-month outcome from this trial. METHODS AND RESULTS: or regurgitant volume >30 mL), and left ventricular ejection fraction between 15% and 40% to undergo percutaneous valve repair plus medical treatment (intervention group, n = 152) or medical treatment alone (control group, n = 152). The primary efficacy outcome was the composite of all-cause death and unplanned hospitalization for heart failure at 12 months. At 24 months, all-cause death and unplanned hospitalization for heart failure occurred in 63.8% of pa

Source type
Peer-reviewed study
DOI
10.1002/ejhf.1616
Catalogue ID
SNmojbir9c-ig8zcn
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