Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac surgery

Giuseppe Filiberto Serraino, Michele Provenzano, Federica Jiritano, Ashour Michael, Nicola Ielapi, Pasquale Mastroroberto, Michele Andreucci, Raffaele Serra

PLoS ONE · 2021

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Summary

BACKGROUND: Acute Kidney Injury (AKI) represents a clinical condition with poor prognosis. The incidence of AKI in hospitalized patients was about 22-57%. Patients undergoing cardiac surgery (CS) are particularly exposed to AKI because of the related oxidative stress, inflammation and ischemia-reperfusion damage. Hence, the risk profile of patients undergoing CS who develop AKI and who are consequently at increased mortality risk deserves further investigation. METHODS: We designed a retrospective study examining consecutive patients undergoing any type of open-heart surgery from January to December 2018. Patients with a history of AKI were excluded. AKI was diagnosed according to KDIGO criteria. Univariate associations between clinical variables and AKI were tested using logistic regressi

Source type
Peer-reviewed study
DOI
10.1371/journal.pone.0252209
Catalogue ID
SNmojg03kb-kdv8da
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