Enoch Akowuah, Rebecca Maier, Helen Hancock, Ehsan Kharatikoopaei, Luke Vale, Cristina Fernandez-García, Emmanuel Ogundimu, Janelle Wagnild, Ayesha Mathias, Zoe Walmsley, Nicola Howe, Adetayo Kasim, Richard Graham, Gavin J. Murphy, Joseph Zacharias, UK Mini Mitral Trial Investigators, Simon Kendall, Andrew Goodwin, Antony Walker, Grzegorz Łaskawski, Paul Modi, Mark Pullan, Dimitrios Pousios, Andrew D Muir, Roberto Casula, Prakesh Punjabi, Hunaid A. Vohra, Massimo Caputo, Franco Ciulli, Șerban Stoica, Vipin Zamvar, Renzo Pessotto, Ranjit Deshpande, Olaf Wendler, Max Baghai, Clinton Lloyd, Malcolm Dalrympole-Hay, Jonathan Unsworth‐White, Toufan Bahrami, Sunil Bhudia, Fabio De Robertis, Luke Rogers, Bilal H. Kirmani, Abdelrahman Abdelbar, Sara O’Rourke, Inderpaul Birdi, Sudhir Bhusari, Hasnat Khan

doi:10.1001/jama.2023.7800

Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair

Enoch Akowuah, Rebecca Maier, Helen Hancock, Ehsan Kharatikoopaei, Luke Vale, Cristina Fernandez-García, Emmanuel Ogundimu, Janelle Wagnild, Ayesha Mathias, Zoe Walmsley, Nicola Howe, Adetayo Kasim, Richard Graham, Gavin J. Murphy, Joseph Zacharias, UK Mini Mitral Trial Investigators, Simon Kendall, Andrew Goodwin, Antony Walker, Grzegorz Łaskawski, Paul Modi, Mark Pullan, Dimitrios Pousios, Andrew D Muir, Roberto Casula, Prakesh Punjabi, Hunaid A. Vohra, Massimo Caputo, Franco Ciulli, Șerban Stoica, Vipin Zamvar, Renzo Pessotto, Ranjit Deshpande, Olaf Wendler, Max Baghai, Clinton Lloyd, Malcolm Dalrympole-Hay, Jonathan Unsworth‐White, Toufan Bahrami, Sunil Bhudia, Fabio De Robertis, Luke Rogers, Bilal H. Kirmani, Abdelrahman Abdelbar, Sara O’Rourke, Inderpaul Birdi, Sudhir Bhusari, Hasnat Khan

JAMA · 2023

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Summary

Importance: The safety and effectiveness of mitral valve repair via thoracoscopically-guided minithoracotomy (minithoracotomy) compared with median sternotomy (sternotomy) in patients with degenerative mitral valve regurgitation is uncertain. Objective: To compare the safety and effectiveness of minithoracotomy vs sternotomy mitral valve repair in a randomized trial. Design, Setting, and Participants: A pragmatic, multicenter, superiority, randomized clinical trial in 10 tertiary care institutions in the UK. Participants were adults with degenerative mitral regurgitation undergoing mitral valve repair surgery. Interventions: Participants were randomized 1:1 with concealed allocation to receive either minithoracotomy or sternotomy mitral valve repair performed by an expert surgeon. Main Out

Source type: Peer-reviewed study
DOI: 10.1001/jama.2023.7800
Catalogue ID: SNmojg0862-6w6vrs

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