Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Effect of intraoperative haemoadsorption therapy on cardiac surgery for active infective endocarditis with confirmed<i>Staphylococcus aureus</i>bacteraemia

Zaki Haidari, Spela Leiler, Hazem Mamdooh, Matthias Fittkau, Kristina Boss, Bartosz Tyczynski, Matthias Thielmann, Erik Bagaev, Mohamed El Gabry, Daniel Wendt, Andreas Kribben, Thomas Bertsch, Arjang Ruhparwar, Theodor Fischlein, Jurij Matija Kališnik

Interdisciplinary CardioVascular and Thoracic Surgery · 2023

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Summary

OBJECTIVES: Sepsis caused by infective endocarditis (IE), due to Staphylococcus aureus, is associated with significant morbidity and mortality. Blood purification using haemoadsorption (HA) may attenuate the inflammatory response. We investigated the effect of intraoperative HA on postoperative outcomes in S. aureus IE. METHODS: Patients with confirmed S. aureus IE undergoing cardiac surgery were included in a dual-centre study between January 2015 and March 2022. Patients treated with intraoperative HA (HA group) were compared to patients not treated with HA (control group). The primary outcome was vasoactive-inotropic score within the first 72 h postoperatively and secondary outcomes were sepsis-related mortality (SEPSIS-3 definition) and overall mortality at 30 and 90 days. RESULTS: No

Source type
Peer-reviewed study
DOI
10.1093/icvts/ivad010
Catalogue ID
SNmojj25pz-en9k21
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