Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Nanocurcumin in myocardial infarction therapy: emerging trends and future directions

Mei Lv, Qing Sun, YU Yi-lin, Jinwei Bao

Frontiers in Bioengineering and Biotechnology · 2025

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Summary

Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide. Curcumin has been observed to significantly reduce pathological processes associated with MI. Its clinical application is limited due to its low bioavailability, rapid degradation, and poor solubility. Advancements in nanotechnology can be used to enhance its therapeutic potentials in MI. Curcumin nano-formulation enhances its solubility, stability, and bioavailability, allowing more precise delivery to ischemic cardiac tissue. Curcumin nanoparticles have been observed to successfully reduce infarct size, maintain heart function by modulating essential molecular pathways in MI. Its liposomal formulations provide sustained release and higher tissue penetration with improved pharmacokinetics and enhanced th

Source type
Peer-reviewed study
DOI
10.3389/fbioe.2024.1511331
Catalogue ID
SNmojj260h-utpyzj
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