Biophysical insights into the relationship between plasma viscosity and atherogenic risk factors among patients who underwent CABG surgery

Summary

Plasma viscosity (PV) is an important determinant of blood flow and hemorheological behavior. Plasma plays a crucial role behaving as an interface between blood and vessel wall. Disturbed blood flow in atherosclerotic arteries, together with elevated plasma fibrinogen and endothelial dysfunction, may trigger mechanical stress on endothelial cells, from which nitric oxide (NO) is secreted. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase enzyme, is an increased marker for atherosclerosis. The present study was designed to investigate the relationship between PV and atherogenic risk factors in severe atherosclerotic patients underwent coronary artery bypass grafting surgery (CABG). Twenty-three male patients with severe atherosclerosis who underwent CABG were divide