Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Advancing cellulose degradation through synthetic biology: engineered pathways and microbial systems for sustainable biomass conversion

Xingqi Liu, Jianping Quan, Ying Li, Xiao‐Fan Wang, Jiangchao Zhao

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · 2026

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Summary

Fiber, the most abundant organic polymer in nature, is widely recognized as a foundational sustainable material with diverse applications across industrial, medical, and consumer domains. Owing to its renewability and widespread availability, it also serves as a critical alternative energy source in agriculture, enabling more sustainable livestock production through the efficient conversion of fibrous feedstuffs, thereby supporting the principles of a circular bioeconomy. Cellulose, which constitutes up to 80% of plant fiber, contains tightly packed crystalline regions that confer strong resistance to microbial degradation. Other key obstacles to efficient cellulose digestion in the gut include the absence of critical cellulolytic genes, low enzymatic activity, a lack of natural activators

Source type
Peer-reviewed study
DOI
10.1186/s40104-025-01328-0
Catalogue ID
SNmok1w78w-p0mo0g
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