Pulse Brain · Growing Health Evidence Index
Peer-reviewed

Glyphosate resistance as a potential driver for the dissemination of multidrug-resistant clinical strains

Camila A. Knecht, Barbara Prack McCormick, Verónica E. Álvarez, Adrián Gonzales Machuca, Fernanda Buzzola, Julio Fuchs, Pablo Salgado, Josefina Campos, Jochen A. Müller, María Paula Quiroga, Daniela Centrón

Frontiers in Microbiology · 2026

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Summary

The rise of antimicrobial resistance (AMR) constitutes a serious threat to global health. Environmental bacterial communities are a key reservoir of AMR genes (ARGs) that can spread to clinical pathogens. Biocides, which include broad-spectrum herbicides, can co-select for ARGs, posing a potential driver for AMR spread. Glyphosate, the world's most widely used herbicide with known bactericidal properties, targets the shikimate pathway and may thus exert selective pressure favoring resistant bacteria, potentially elevating clinical AMR risk from a One Health perspective. We assessed glyphosate resistance in multidrug-resistant (MDR) species isolated from nosocomial infections. Furthermore, we investigated the relationship between glyphosate-resistant environmental species and clinically rel

Source type
Peer-reviewed study
DOI
10.3389/fmicb.2026.1740431
Catalogue ID
SNmok1w8ws-x3fj6n
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