Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

The diversity and applications of microbial iron metabolism and iron-containing proteins

Haichun Gao, Ingrid Span

Communications Biology · 2025

Read source ↗ All evidence

Summary

This review collection synthesises research on microbial iron metabolism and iron-containing proteins, spanning hemoproteins, iron-sulfur cluster proteins, and regulatory mechanisms governing iron and heme homeostasis. The work addresses both molecular mechanisms and ecological consequences of iron metabolism in microbial communities and host–microbe interactions. The collection likely integrates findings across microbiology, biochemistry, and systems ecology relevant to understanding iron cycling in biological systems.

Regional applicability

This is a mechanistic review of fundamental microbial iron biochemistry without explicit geographic focus. Findings on microbial iron metabolism are broadly applicable to United Kingdom soil and agricultural microbiology research, though the review's primary value lies in advancing fundamental understanding rather than direct policy or farming practice application.

Key measures

Protein structure and function of hemoproteins and iron-sulfur cluster proteins; iron and heme homeostasis mechanisms; ecological and biochemical interactions in microbial communities

Outcomes reported

This collection reviews research on hemoproteins, iron-sulfur cluster proteins, and other iron-containing proteins, alongside mechanisms of iron and heme homeostasis and their regulation. The work examines ecological impacts of iron and heme metabolism on interactions between microbial communities and host organisms.

Theme
General food systems / other
Subject
Soil biology & microbiology
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.1038/s42003-024-07373-1
Catalogue ID
SNmonut3s2-8h5pvb

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.