Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Microbial metal physiology: ions to ecosystems

John D. Helmann

Nature Reviews Microbiology · 2025

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Summary

This Nature Reviews Microbiology article by Helmann (2025) provides a comprehensive review of microbial metal physiology, examining how microorganisms sense, transport and utilise metal ions from the molecular level through to ecosystem consequences. The paper synthesises mechanistic understanding of metal-dependent processes—including metalloproteins, homeostasis and stress responses—and contextualises these within broader soil and environmental cycling. As a review in a leading microbiology journal, it is likely to inform understanding of soil microbial function relevant to nutrient availability and cycling in agricultural systems.

Regional applicability

This is a fundamental microbiology review with broad applicability. Findings on microbial metal physiology principles are likely transferable to United Kingdom soil conditions, though specific ecosystem outcomes will depend on local soil chemistry, pH, parent material and management practices. The review may inform evidence-based soil health assessment and management strategies in UK farming.

Key measures

Not specified in available metadata; likely includes metal uptake kinetics, gene expression, enzyme activity, and ecosystem-level nutrient cycling rates as inferred from title.

Outcomes reported

As suggested by the title, this review likely synthesises current understanding of how microorganisms acquire, regulate and utilise metal ions, and how these processes scale from cellular to ecosystem levels. The paper probably addresses mechanistic links between microbial metal physiology and broader soil and environmental functions.

Theme
Farming systems, soils & land use
Subject
Soil biology & microbiology
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.1038/s41579-025-01213-7
Catalogue ID
SNmonut3s2-v3zk8s

Topic tags

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