Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Profiling Metabolites with Antifungal Activities from Endophytic Plant-Beneficial Strains of Pseudomonas chlororaphis Isolated from Chamaecytisus albus (Hack.) Rothm.

Wojciech Sokołowski, Monika Marek-Kozaczuk, Piotr Sosnowski, Ewa Sajnaga, Monika Elżbieta Jach, Magdalena Anna Karaś

Molecules · 2024

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Summary

This study characterised three endophytic Pseudomonas chlororaphis isolates from Chamaecytisus albus nodules for their biocontrol potential against fungal phytopathogens. Through metabolomic and genetic analyses, the researchers identified that these strains produce multiple bioactive compounds—predominantly phenazine derivatives, diketopiperazines, pyrrolnitrin, and volatile organic compounds—conferring broad-spectrum antifungal activity. The isolates exhibited both biocontrol and plant growth promotion characteristics, positioning them as candidates for sustainable agriculture and postharvest fungicide applications.

Regional applicability

The paper does not specify study geography and is a laboratory characterisation study, limiting direct field applicability assessment. The findings could be relevant to United Kingdom horticultural and arable systems if field trials confirm efficacy under local conditions, particularly for management of common pathogens such as Botrytis and Fusarium.

Key measures

Antagonistic activity against fungal phytopathogens; production of diffusible and volatile antifungal compounds; chromatographic and spectrometric identification (HPTLC, GC-MS, LC-MS/MS); PCR confirmation of phzF, phzO, prnC genes; plant growth promotion properties (HCN, auxin, siderophore, hydrolytic enzyme production; phosphate solubilisation)

Outcomes reported

The study identified and characterised antifungal metabolites produced by three endophytic Pseudomonas chlororaphis isolates, including phenazine derivatives, diketopiperazines, pyrrolnitrin, and volatile compounds. All tested strains demonstrated broad-range antifungal activity against soil-borne phytopathogens (B. cinerea, F. oxysporum, S. sclerotiorum) with varying degrees of antagonism.

Theme
Farming systems, soils & land use
Subject
Soil biology & microbiology
Study type
Research
Study design
Laboratory study with biological, metabolomic, and genetic analyses
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.3390/molecules29184370
Catalogue ID
SNmonut8jw-3r0wd7

Topic tags

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