Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Exploring the Functional Roles of Endophytic Bacteria in Plant Stress Tolerance for Sustainable Agriculture: Diversity, Mechanisms, Applications, and Challenges

Akhila Sen, Johns Saji, Parammal Faseela, Chunquan Zhang, Shibin Mohanan, Ye Xia

Plants · 2026

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Summary

This narrative review examines endophytic bacteria—microorganisms residing within plant tissues without causing pathology—as functional agents for enhancing plant resilience to stress in agricultural systems. The authors synthesise evidence on bacterial diversity across four major phyla and describe multiple mechanistic pathways (immune priming, secondary metabolite production, nutrient cycling) that confer stress tolerance benefits. The review acknowledges substantial promise for sustainable agriculture whilst highlighting critical gaps: plant–microbe interaction complexity, variable efficacy across environments, and the need for improved identification and application methodologies.

UK applicability

Endophytic bacterial inoculants could support UK arable and horticultural production under variable climate and pest pressures, particularly where chemical inputs are restricted or antimicrobial stewardship is prioritised. However, the review indicates that efficacy variability across environmental conditions requires site-specific validation before widespread UK adoption.

Key measures

Diversity of endophytic bacterial phyla; mechanisms of stress tolerance (systemic resistance, bioactive compounds, nutrient transfer); barriers to application across environmental conditions

Outcomes reported

This review synthesises evidence on the diversity of endophytic bacterial taxa (Actinobacteria, Bacteroidetes, Firmicutes, Proteobacteria) and their functional mechanisms in enhancing plant tolerance to biotic and abiotic stresses. It identifies key mechanisms including systemic resistance induction, bioactive compound synthesis, resource competition, and nutrient production, whilst documenting challenges limiting agricultural application.

Theme
Farming systems, soils & land use
Subject
Soil biology & microbiology
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
Global
System type
Laboratory / in vitro
DOI
10.3390/plants15020206
Catalogue ID
SNmoqqt88w-uanzvz

Topic tags

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