Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Towards a spatiotemporally explicit toxicokinetic-toxicodynamic model for earthworm toxicity

Vanessa Roeben, Susanne Oberdoerster, Kim Rakel, Dino Liesy, Yvan Capowiez, Gregor Ernst, Thomas G. Preuß, André Gergs, C. Oberdoerster

The Science of The Total Environment · 2020

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Summary

This paper addresses a critical gap in environmental risk assessment by proposing an integrated modular modelling framework that links exposure and effect assessment for earthworms exposed to pesticides. The framework combines environmental exposure models, trait-based behaviour simulation, toxicokinetic-toxicodynamic (TKTD) modelling, and population models to account for the spatial and temporal scales at which soil organisms experience contaminants. The authors argue this approach will enhance regulatory risk assessment by capturing the dynamic interactions between chemical exposure, organism movement and feeding ecology, and toxicological response.

UK applicability

The modelling framework is directly applicable to UK soil risk assessment under the Environment Agency's pesticide authorisation and monitoring schemes. However, the abstract does not specify whether the case study or model parameterisation was based on UK soil conditions, earthworm species distributions, or climate data, limiting immediate applicability without further scrutiny of the full paper.

Key measures

Spatially and temporally explicit chemical concentrations; environmental variables (temperature, moisture, organic matter content); earthworm feeding and movement behaviour; toxicokinetic-toxicodynamic model outputs; population-level predictions

Outcomes reported

The study developed a conceptual modular modelling framework integrating pesticide exposure assessment, earthworm ecology, and toxicological effects. The approach was illustrated through a case study with an insecticide, demonstrating how spatially and temporally explicit environmental data can be linked to toxicokinetic-toxicodynamic predictions of organism-level effects.

Theme
Farming systems, soils & land use
Subject
Soil biology & microbiology
Study type
Research
Study design
Methodological framework development with case study illustration
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Laboratory / in vitro
DOI
10.1016/j.scitotenv.2020.137673
Catalogue ID
SNmov5ihfp-a2oyp6

Topic tags

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