Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Genomic architecture of adaptive radiation and hybridization in Alpine whitefish

Rishi De‐Kayne, Oliver M. Selz, David A. Marques, David Frei, Ole Seehausen, Philine G. D. Feulner

Nature Communications · 2022

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Summary

This genomic study of Alpine whitefish radiation demonstrates that rapid ecological and morphological diversification is driven by both polygenic allele frequency shifts and a specific high-effect locus (edar), with secondary contact and hybridisation between lake populations contributing to the evolution of species with novel trait combinations. The work illuminates the relative contributions of genome architecture and introgressive hybridisation in fuelling adaptive radiation, a fundamental question in evolutionary biology.

Regional applicability

This study is of limited direct applicability to United Kingdom farming or food production systems, as it focuses on wild Alpine freshwater fish populations and evolutionary genomics rather than agricultural systems, soil health, or nutrient density. However, findings on the interplay between genetic architecture and hybridisation in resource-limited adaptive contexts may inform conservation and breeding programmes for UK freshwater fisheries.

Key measures

Whole-genome sequencing data; allele frequency shifts; edar locus effect size; introgression patterns between species and lake-systems

Outcomes reported

The study examined whole-genome data from 22 whitefish species across six ecomorphs in Alpine lake systems to identify genetic mechanisms underlying rapid diversification. Findings revealed genome-wide allele frequency shifts and a major-effect locus associated with the edar gene, plus evidence of introgression between lake populations facilitating trait evolution.

Theme
General food systems / other
Subject
Aquaculture & fisheries
Study type
Research
Study design
Comparative genomics study
Source type
Peer-reviewed study
Status
Published
Geography
Switzerland
System type
Aquaculture
DOI
10.1038/s41467-022-32181-8
Catalogue ID
SNmp6e6rim-r71ftl

Topic tags

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