Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Dietary phytochemical index and the risk of cancer: a systematic review and meta-analysis

Ahmadirad H, Omrani M, Azmi N, Saeidian AH, Jahromi MK, Mirtavoos-Mahyari H, et al

PLoS ONE · 2025.0

Read source ↗ All evidence

Summary

This systematic review and meta-analysis, published in PLoS ONE in 2025, synthesises evidence on the relationship between the dietary phytochemical index — a tool measuring intake of phytochemical-rich foods — and cancer risk. By pooling data from multiple observational studies, the paper likely finds that higher DPI scores are associated with a reduced risk of certain cancers, though the strength and consistency of this association may vary by cancer type. The review contributes to the evidence base linking plant-rich dietary patterns with protective effects against cancer, whilst acknowledging methodological limitations inherent in observational research.

UK applicability

Whilst the included studies are likely drawn from diverse international populations, the findings are broadly applicable to UK dietary public health policy, particularly in the context of guidance on plant-based diets and cancer prevention issued by bodies such as the NHS and World Cancer Research Fund.

Key measures

Dietary phytochemical index (DPI); cancer risk (odds ratios or relative risks); pooled effect estimates across cancer types

Outcomes reported

The study examined the association between dietary phytochemical index (DPI) scores and the risk of various cancers across multiple populations. It pooled effect estimates from observational studies to assess whether higher phytochemical intake, as measured by the DPI, is associated with reduced cancer incidence.

Theme
Nutrition & health
Subject
Diet, phytonutrients & cancer prevention
Study type
Meta-analysis
Study design
Systematic review and meta-analysis
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1371/journal.pone.0319591
Catalogue ID
WP0124

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.