Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

High bioavailability of reduced iron added to UK flour

Roe MA, Fairweather-Tait SJ

Lancet · 1999.0

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Summary

This short communication published in The Lancet presents findings on the bioavailability of reduced (elemental) iron used to fortify UK wheat flour under the Bread and Flour Regulations. The authors, both recognised researchers in iron nutrition, challenge the prevailing assumption that reduced iron is poorly absorbed, suggesting its bioavailability may be substantially higher than previously estimated. The findings have implications for assessments of dietary iron adequacy in populations consuming fortified bread products.

UK applicability

Directly applicable to UK policy and practice, as UK flour fortification with reduced iron is mandated under the Bread and Flour Regulations 1998; the findings inform whether this form of iron is an effective vehicle for addressing iron deficiency in the UK population.

Key measures

Iron bioavailability (fractional iron absorption, %); likely serum ferritin or erythrocyte incorporation of labelled iron

Outcomes reported

The study measured the bioavailability of reduced iron added to UK white flour, likely using isotopic tracer or in vitro/in vivo methods to assess absorption relative to other iron forms. It reportedly found that reduced iron in fortified flour has higher bioavailability than previously assumed.

Theme
Nutrition & health
Subject
Micronutrient bioavailability & food fortification
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
UK
System type
Food supply chain
DOI
10.1016/s0140-6736(99)01369-0
Catalogue ID
WP0129

Topic tags

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