Summary
The WCRF/AICR Continuous Update Project (CUP) is an ongoing programme of systematic literature reviews examining the relationships between diet, nutrition, physical activity, body weight, and cancer risk. Drawing on large bodies of epidemiological and mechanistic evidence, the project produces regularly updated expert reports and cancer-specific summaries with graded evidence judgements. It represents one of the most comprehensive and authoritative global syntheses of diet-cancer evidence available to researchers, clinicians, and policymakers.
UK applicability
The CUP findings are directly applicable to UK public health policy and dietary guidance, and have informed Cancer Research UK and NHS recommendations on cancer prevention. The WCRF has a significant UK presence, and its recommendations align closely with UK dietary guidelines and national cancer prevention strategies.
Key measures
Cancer risk estimates (relative risk, hazard ratios); strength-of-evidence grading; dietary exposure assessments; physical activity levels; body fatness measures (BMI, waist circumference)
Outcomes reported
The project synthesises evidence on associations between dietary patterns, specific foods and nutrients, physical activity, body weight, and cancer risk across multiple cancer types. It reports graded evidence judgements on the strength of causal relationships between lifestyle factors and cancer incidence.
Topic tags
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