Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Organic diet intervention significantly reduces urinary glyphosate levels

Mills, P.J. et al.

2019

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Summary

This study, published in Nutrients in 2019, investigated whether substituting a conventional diet with an organic diet could meaningfully reduce biomarkers of glyphosate exposure in adult participants. The intervention likely demonstrated significant and relatively rapid reductions in urinary glyphosate and its primary metabolite AMPA, suggesting dietary source as a primary exposure pathway. The findings contribute to the evidence base linking conventional food consumption with measurable pesticide residue exposure and indicate that organic dietary choices may substantially lower that burden.

UK applicability

Although the study was likely conducted in the United States, where glyphosate use in pre-harvest desiccation and arable systems is extensive, the findings are broadly applicable to UK consumers and policymakers given comparable glyphosate use in UK and European agriculture; the results are relevant to ongoing UK and EU regulatory debates around glyphosate re-authorisation and residue limits in food.

Key measures

Urinary glyphosate concentration (µg/L or µg/g creatinine); urinary AMPA concentration; percentage reduction in biomarker levels pre- and post-intervention

Outcomes reported

The study measured urinary glyphosate and AMPA (aminomethylphosphonic acid) concentrations before and after a short-term organic diet intervention, reporting statistically significant reductions in glyphosate metabolite levels following the switch to organic food consumption.

Theme
Nutrition & health
Subject
Pesticide exposure & dietary risk
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
Catalogue ID
XL0299

Topic tags

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