Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Effects on BP of dietary patterns: DASH

Sacks, F.M. et al.

2001

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Summary

This landmark randomised controlled trial, published in the New England Journal of Medicine, examined the combined effects of the DASH dietary pattern and graded sodium reduction on blood pressure. The study found that both reduced sodium intake and adherence to the DASH diet independently lowered blood pressure, with the greatest reductions observed when both interventions were combined. The findings provided strong clinical evidence supporting dietary modification as a non-pharmacological strategy for blood pressure management.

UK applicability

Although conducted in the United States, the DASH dietary principles — emphasising fruits, vegetables, whole grains, and low-fat dairy whilst limiting sodium and saturated fat — are broadly consistent with UK dietary guidelines and are referenced in NHS and NICE guidance on cardiovascular disease prevention. The findings are widely applicable to UK clinical and public health practice.

Key measures

Systolic blood pressure (mmHg); diastolic blood pressure (mmHg); sodium intake levels (higher, intermediate, lower); dietary pattern (DASH vs. control diet)

Outcomes reported

The study examined the effect of the DASH dietary pattern and sodium reduction on systolic and diastolic blood pressure across participants with and without hypertension. It reported dose-response reductions in blood pressure associated with lower sodium intake and adherence to the DASH diet.

Theme
Nutrition & health
Subject
Dietary patterns & cardiovascular health
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
Catalogue ID
XL0379

Topic tags

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