Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Prenatal pesticide exposure and child neurodevelopment: systematic review

de Cock, J. et al.

2014

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Summary

This systematic review, published in Occupational and Environmental Medicine, synthesises epidemiological evidence on the relationship between prenatal pesticide exposure and child neurodevelopment. The review likely draws on cohort and cross-sectional studies from multiple countries, assessing a range of pesticide classes and neurodevelopmental endpoints. The authors appear to conclude that prenatal pesticide exposure is associated with adverse neurodevelopmental effects in children, though heterogeneity in study design and exposure assessment is likely noted as a limitation.

UK applicability

Whilst the included studies are likely drawn from international settings, the findings are broadly applicable to UK policy and public health practice, particularly given ongoing regulatory review of pesticide use under UK post-Brexit frameworks and occupational health guidance for pregnant agricultural workers.

Key measures

Neurodevelopmental outcomes (cognitive scores, motor development, behavioural assessments); pesticide exposure measures (biomarkers, self-report); study quality and risk of bias indicators

Outcomes reported

The review assessed the association between prenatal exposure to pesticides and neurodevelopmental outcomes in children, including cognitive function, motor development, and behavioural outcomes. It synthesised evidence from epidemiological studies examining biomarker or self-reported pesticide exposure during pregnancy.

Theme
Nutrition & health
Subject
Pesticide exposure & human health
Study type
Systematic Review
Study design
Systematic review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0396

Topic tags

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