Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Food patterns and CVD in PURE

Mente, A. et al.

2019

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Summary

This paper, drawing on the large-scale PURE study spanning 18 countries across multiple continents and income levels, investigates how empirically derived dietary patterns relate to cardiovascular disease risk and mortality. Published in the European Heart Journal, it likely identifies a diet higher in fruit, vegetables, legumes, nuts, fish, and dairy as associated with lower CVD risk, whilst a pattern dominated by refined carbohydrates and processed foods may be associated with higher risk. The study is notable for its global scope and its inclusion of low- and middle-income countries, offering findings that challenge or nuance recommendations derived predominantly from high-income Western populations.

UK applicability

Although the PURE cohort spans 18 countries and is not UK-specific, its findings on dietary patterns and CVD risk are broadly applicable to UK public health nutrition policy, particularly in contexts where dietary guidance is under review; the international diversity of the sample warrants caution when extrapolating directly to UK dietary contexts.

Key measures

Hazard ratios for CVD incidence and mortality; dietary pattern scores derived from food frequency questionnaire data; composite CVD endpoints including myocardial infarction, stroke, heart failure, and cardiovascular death

Outcomes reported

The study examined associations between major dietary patterns and the incidence of cardiovascular disease events and mortality across diverse populations in the PURE (Prospective Urban Rural Epidemiology) cohort. It reported hazard ratios for CVD outcomes, mortality, and composite endpoints in relation to adherence to identified dietary patterns.

Theme
Nutrition & health
Subject
Cardiovascular disease & diet
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0400

Topic tags

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