Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Polyphenols and microbiota

Wan, M.L.Y. et al.

2021

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Summary

This review, published in Critical Reviews in Food Science and Nutrition (2021, 61(4): 690–711), examines the bidirectional relationship between dietary polyphenols and the gut microbiome. It likely synthesises evidence on how gut bacteria transform polyphenols into bioactive metabolites and how polyphenol consumption may selectively modulate microbial populations, with implications for host metabolic and immune health. The paper contributes to the growing body of literature linking dietary phytochemicals to microbiome-mediated health effects.

UK applicability

Findings are broadly applicable to UK public health and dietary guidance contexts, particularly given UK interest in gut health, dietary fibre, and plant-rich diets; however, as an international narrative review, specific population-level recommendations would require corroboration with UK-based cohort data.

Key measures

Gut microbiota composition; microbial metabolite profiles (e.g. short-chain fatty acids); polyphenol bioavailability and biotransformation; markers of gut barrier integrity and inflammation

Outcomes reported

The review examines how dietary polyphenols are metabolised by gut microbiota and how, in turn, polyphenols modulate microbial composition and activity. It likely reports on changes in microbial diversity, short-chain fatty acid production, and downstream effects on host health outcomes.

Theme
Nutrition & health
Subject
Gut microbiome & dietary phytochemicals
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0618

Topic tags

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