Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Weisberger JH. 1991. Nutritional approach to cancer prevention with emphasis on vitamins, antioxidants, and carotenoids. American Journal of Clinical Nutrition 53(1):226-237

1991

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Summary

This narrative review by Weisburger (note: likely a variant spelling of Weisburger, a prominent cancer research figure) synthesises evidence available in the early 1990s on the role of nutritional factors — particularly vitamins, antioxidants and carotenoids — in the prevention of cancer. The paper likely addresses mechanisms by which these dietary compounds may inhibit carcinogenesis, drawing on both epidemiological associations and laboratory findings. It represents an early and influential contribution to the field of nutritional oncology and preventive medicine.

UK applicability

Although the paper is international in scope and not UK-specific, its findings on dietary micronutrients and cancer risk are broadly applicable to UK public health and dietary guidance, and would have informed subsequent UK and European cancer prevention recommendations.

Key measures

Cancer incidence and risk reduction associated with dietary antioxidant intake; levels of vitamins A, C, E and carotenoids in relation to cancer outcomes

Outcomes reported

The paper examines the evidence linking dietary intake of vitamins, antioxidants and carotenoids to reduced cancer risk, likely drawing on epidemiological and experimental data available up to 1991. It reports on the potential protective mechanisms of specific micronutrients against carcinogenesis.

Theme
Nutrition & health
Subject
Diet, micronutrients & cancer prevention
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
Catalogue ID
XL0891

Topic tags

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