Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Un caso familiar de microduplicación distal 22q11.2

L Domingo Comeche, MJ Rivero Martín, S de las Heras Ibarra, Mary C. Martin, B García Pimentel

Acta pediátrica española/Acta pediátrica española · 2020

All evidence

Summary

This case report, as suggested by the title and journal context, describes a family with microduplication of the distal 22q11.2 chromosomal region. The authors document the genetic finding and clinical presentation across affected family members. The work appears to contribute to understanding of rare chromosomal variations and their familial inheritance patterns in paediatric populations.

UK applicability

The findings have limited direct application to UK agricultural or food systems research. Clinical genetic case reports of this type may inform paediatric diagnostic protocols in the UK National Health Service, but fall outside the scope of farming systems and nutrient density research.

Key measures

Chromosomal microduplication identified through cytogenetic or molecular analysis; phenotypic and clinical features in family members

Outcomes reported

The study reports a clinical case of familial microduplication in the distal 22q11.2 chromosomal region, examining genetic inheritance patterns and associated phenotypic characteristics in affected family members.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Case report
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
Catalogue ID
BFmobghmm4-dx534j

Topic tags

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