Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation

Philippe B. Bertrand, Jessica Overbey, Xin Zeng, Robert A. Levine, Gorav Ailawadi, Michael A. Acker, Peter K. Smith, Vinod H. Thourani, Emilia Bagiella, Marissa A. Miller, Lopa Gupta, Michael J. Mack, A. Marc Gillinov, Gennaro Giustino, Alan J. Moskowitz, Annetine C. Gelijns, Michael E. Bowdish, Patrick T. O’Gara, James S. Gammie, Judy Hung, Marissa A. Miller, Wendy C. Taddei-Peters, Dennis Buxton, Ron Caulder, Nancy L. Geller, David Gordon, Neal O. Jeffries, Albert Lee, Claudia S. Moy, Ilana Kogan Gombos, Jennifer Ralph, Richard D. Weisel, Timothy J. Gardner, Patrick T. O’Gara, Eric A. Rose, Annetine C. Gelijns, Michael K. Parides, Deborah D. Ascheim, Alan J. Moskowitz, Emilia Bagiella, Ellen Moquete, Helena Chang, Melissa Chase, James Foo, Yingchun Chen, Seth Goldfarb, Lopa Gupta, Katherine Kirkwood, Edlira Dobrev, Ron Levitan, Karen O’Sullivan, Jessica Overbey, Milerva Santos, Deborah Williams, Michael Weglinski, Paula Williams, Carrie Wood, Xia Ye, Sten Lyager Nielsen, Henrik Wiggers, Henning Malgaard, Michael Mack, Tracine Adame, Natalie Settele, Jenny Adams, William Ryan, Robert L. Smith, Paul Grayburn, Frederick Y. Chen, Anju Nohria, Lawrence Cohn, Prem Shekar, Sary Aranki, Gregory Couper, Michael Davidson, R. Morton Bolman, Anne Burgess, Debra Conboy, Rita Lawrence, Nicolas Noiseux, Louis-Mathieu Stevens, Ignacio Prieto, Fadi Basile, Joannie Dionne, Julie Fecteau, Eugene H. Blackstone, A. Marc Gillinov, Pamela Lackner, Leoma Berroteran, Diana Dolney, Suzanne Fleming, Roberta Palumbo, Christine Whitman, Kathy Sankovic, Denise Kosty Sweeney, Carrie Geither, Kristen Doud, Gregory Pattakos, Pamela A. Clarke, Michael Argenziano

Journal of the American College of Cardiology · 2021

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Summary

This multi-institutional prospective observational cohort study (as suggested by extensive authorship and Journal of the American College of Cardiology publication) examined the natural history of tricuspid regurgitation in patients undergoing surgical repair for ischaemic mitral regurgitation. The work characterised post-operative TR development and progression over follow-up, addressing an important clinical question regarding optimal surgical strategy and the need for concomitant tricuspid valve intervention in patients with combined mitral and tricuspid valve pathology.

UK applicability

Findings from this cardiothoracic surgical outcome study would be applicable to UK cardiac surgery practice and patient management protocols; however, applicability depends on whether the cohort included UK centres or comparable healthcare systems.

Key measures

Tricuspid regurgitation severity and progression; timing and rates of TR development post-operatively; patient outcomes and need for subsequent tricuspid intervention

Outcomes reported

The study characterised the natural history and progression of tricuspid regurgitation (TR) in patients undergoing surgical repair for ischaemic mitral regurgitation. Findings likely quantified rates of post-operative TR development and identified clinical factors associated with progression.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jacc.2020.11.066
Catalogue ID
BFmokjo9ap-3pm1hz

Topic tags

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