Summary
This analysis of 214 patients from two cardiothoracic surgical trials examined whether mismatch between left ventricular size and mitral valve ring size predicts recurrent mitral regurgitation after restrictive ring annuloplasty. The study found that larger left ventricular end-systolic dimension relative to ring size independently predicted one-year mitral regurgitation recurrence, even after adjustment for baseline ejection fraction and regurgitation severity. The findings suggest that consideration of ventricular-to-ring sizing ratios, rather than ring size alone based on intertrigonal distance, may improve surgical outcomes and guide selection of repair versus replacement strategies.
UK applicability
The findings are relevant to cardiac surgery practice in the United Kingdom, as they provide evidence-based guidance for selecting appropriately sized annuloplasty rings in ischaemic mitral regurgitation repair. However, applicability depends on whether UK surgical cohorts and imaging protocols are comparable to those in the enrolled trials.
Key measures
Left ventricular end-diastolic dimension, left ventricular end-systolic dimension, ring size, LV-MV ring mismatch ratio (LVESd/ring size), recurrent moderate or greater mitral regurgitation at 1 year
Outcomes reported
The study measured the rate of recurrent moderate or severe mitral regurgitation at one year following ring annuloplasty in patients with ischaemic mitral regurgitation, and evaluated the association between left ventricular to mitral valve ring size mismatch and recurrence.
Topic tags
Dig deeper with Pulse AI.
Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.