Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Hybrid Coronary Revascularization for the Treatment of Multivessel Coronary Artery Disease

John D. Puskas, Michael E. Halkos, Joseph J. DeRose, Emilia Bagiella, Marissa A. Miller, Jessica Overbey, Johannes Bonatti, V.S. Srinivas, Mark R. Vesely, Francis P. Sutter, Janine Lynch, Katherine Kirkwood, Timothy Shapiro, Konstantinos Dean Boudoulas, Juan A. Crestanello, Thomas Gehrig, Peter K. Smith, Michael Ragosta, Steven J. Hoff, David Zhao, Annetine C. Gelijns, Wilson Y. Szeto, Giora Weisz, Michael Argenziano, Thomas A. Vassiliades, Henry Liberman, William Matthai, Deborah D. Ascheim

Journal of the American College of Cardiology · 2016

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Summary

This randomised controlled trial, published in the Journal of the American College of Cardiology in 2016, evaluated hybrid coronary revascularisation—a combined approach using minimally invasive direct coronary artery bypass grafting and percutaneous coronary intervention—for patients with multivessel coronary artery disease. The study, led by Puskas and collaborators across multiple US cardiac centres, appears to assess whether this hybrid strategy offers clinical benefits compared to conventional approaches. The findings contribute to the evidence base for interventional cardiology practice in managing complex coronary disease.

UK applicability

Although this is a US-based clinical trial, the findings are relevant to UK cardiac surgery and interventional cardiology practice, where hybrid revascularisation techniques are increasingly adopted in specialist centres. Implementation would depend on NHS resource allocation and training availability in participating hospitals.

Key measures

Major adverse cardiovascular events, procedural success rates, follow-up clinical outcomes, safety metrics

Outcomes reported

The study evaluated the efficacy and safety of hybrid coronary revascularisation (combining minimally invasive direct coronary artery bypass with percutaneous coronary intervention) for treating multivessel coronary artery disease. Outcomes measured likely included procedural success, major adverse cardiovascular events, and clinical outcomes at follow-up.

Theme
Nutrition & health
Subject
Other / interdisciplinary
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jacc.2016.05.032
Catalogue ID
BFmokjo9ap-ixyf01

Topic tags

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