Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Gait Speed and Operative Mortality in Older Adults Following Cardiac Surgery

Jonathan Afilalo, Sunghee Kim, Sean M. O’Brien, James M. Brennan, Fred H. Edwards, Michael J. Mack, James B. McClurken, Joseph C. Cleveland, Peter K. Smith, David M. Shahian, Karen P. Alexander

JAMA Cardiology · 2016

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Summary

This prospective cohort study of 15,171 older adults (median age 71 years) undergoing cardiac surgery at 109 centres demonstrates that slower gait speed independently predicts operative mortality and morbidity, beyond existing risk stratification models. Patients in the slowest gait speed tertile (<0.83 m/s) had 3.16-fold increased odds of 30-day operative mortality compared to the fastest tertile (>1.00 m/s). The findings suggest that simple functional assessment via gait speed may enhance risk prediction for cardiac surgical candidates, though the absolute improvement to existing models was modest.

UK applicability

The findings are applicable to UK cardiac surgery practice, as gait speed testing is a low-cost, non-invasive assessment feasible in pre-operative evaluation. Implementation could support shared decision-making with older patients considering cardiac surgery, though adoption would require integration into existing UK pre-operative assessment pathways and validation in UK populations.

Key measures

5-metre gait speed (m/s); 30-day operative mortality; composite outcome of mortality or major morbidity; odds ratios with 95% confidence intervals; C statistic; integrated discrimination improvement

Outcomes reported

The study measured 30-day all-cause operative mortality and a composite outcome of mortality or major morbidity during index hospitalisation in older adults undergoing cardiac surgery. Gait speed was assessed via a 5-metre walk test and analysed for its association with surgical outcomes.

Theme
Nutrition & health
Subject
Other / interdisciplinary
Study type
Research
Study design
Prospective observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1001/jamacardio.2016.0316
Catalogue ID
BFmokjo9ap-wtgkgb

Topic tags

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