Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Impact of Microbiological Organism Type on Surgically Managed Endocarditis

Judson B. Williams, Asad A. Shah, Shuaiqi Zhang, Sin‐Ho Jung, Babatunde A. Yerokun, Sreekanth Vemulapalli, Peter K. Smith, James S. Gammie, Jeffrey G. Gaca

The Annals of Thoracic Surgery · 2019

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Summary

This retrospective cohort study from a thoracic surgery centre examined how the causative microorganism in surgically managed infective endocarditis influenced postoperative outcomes. The analysis stratified patients by organism type—as suggested by the title, comparing outcomes across different bacterial or fungal pathogens. The findings may inform organism-specific surgical risk stratification and treatment planning in endocarditis.

UK applicability

Surgical management protocols for infective endocarditis are broadly similar across high-income healthcare systems; however, UK applicability depends on whether causative organism epidemiology (e.g. prevalence of MRSA, streptococci, or prosthetic-device-related pathogens) differs materially from the US cohort studied.

Key measures

Surgical outcomes (mortality, morbidity, complications) stratified by organism type; patient demographics and clinical characteristics

Outcomes reported

The study examined surgical outcomes in endocarditis patients stratified by the microbiological organism causing infection. Comparative analysis of mortality, morbidity and clinical course was likely reported across different pathogen types.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.athoracsur.2019.04.025
Catalogue ID
BFmommphdp-bzz1pc

Topic tags

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