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Tier 4 — Narrative / commentaryPeer-reviewed

ESMO Clinical Practice Guideline interim update on first-line therapy in advanced urothelial carcinoma

Thomas Powles, Joaquim Bellmunt, Éva Compérat, Maria De Santis, Robert Huddart, Yohann Loriot, Andrea Necchi, Begoña P. Valderrama, Alain Ravaud, Shahrokh F. Shariat, Bernadett Szabados, Michiel S. van der Heijden, Silke Gillessen

Annals of Oncology · 2024

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Summary

This ESMO clinical practice guideline interim update synthesises evidence on first-line systemic therapy for patients with advanced urothelial carcinoma. The guideline, authored by an international panel of specialists, reflects current best practice recommendations as of 2024. The update is intended to support clinicians and multidisciplinary teams in treatment decision-making for this patient population.

UK applicability

As an ESMO guideline with European authorship, the recommendations are directly applicable to UK oncology practice and NHS treatment protocols. The evidence base and therapeutic algorithms should align with UK standard-of-care pathways for advanced urothelial cancer.

Key measures

Treatment response, survival outcomes, and safety profiles of first-line therapeutic agents in advanced urothelial carcinoma (as typical for ESMO clinical practice guidelines)

Outcomes reported

The guideline update addresses first-line therapeutic recommendations for patients with advanced urothelial carcinoma, synthesising evidence on treatment efficacy and safety. As suggested by the title, the update reflects current evidence on systemic therapy options for this cancer type.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Guideline
Study design
Guideline
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1016/j.annonc.2024.03.001
Catalogue ID
BFmommpjky-qyf0ht

Topic tags

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