Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Redefining adequate margins in oral squamous cell carcinoma: outcomes from close and positive margins

Prateek Jain, Rajeev Sharan, Kapila Manikantan, Gary M. Clark, Sanjoy Chatterjee, Indranil Mallick, Paromita Roy, Pattatheyil Arun

European Archives of Oto-Rhino-Laryngology · 2020

Read source ↗ All evidence

Summary

This clinical study, published in a peer-reviewed otolaryngology journal, appears to re-examine the conventional paradigm of surgical margin adequacy in oral squamous cell carcinoma, comparing outcomes between patients with close or positive margins. The research suggests that margin definitions may warrant redefinition based on actual patient outcomes rather than historical standards. The findings carry implications for surgical practice and margin assessment protocols in head and neck oncology.

UK applicability

UK head and neck cancer services operate within established NICE guidance and multidisciplinary team protocols for oral cancer management. If this study challenges standard margin definitions, findings would require evaluation against UK practice standards and integration with existing surgical protocols.

Key measures

Surgical margin status (close vs. positive), recurrence rates, survival outcomes

Outcomes reported

The study examined surgical outcomes and recurrence rates in oral squamous cell carcinoma patients treated with close or positive margins, as suggested by the title.

Theme
Nutrition & health
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
India
System type
Human clinical
DOI
10.1007/s00405-019-05779-w
Catalogue ID
BFmommplae-bt65pp

Topic tags

Pulse AI · ask about this record

Dig deeper with Pulse AI.

Pulse AI has read the whole catalogue. Ask about this record, its theme, or how the findings apply to UK farming and policy — every answer cites the underlying studies.