Summary
This pilot study evaluated a collagen/oxidised regenerated cellulose (C/ORC) matrix dressing applied to split-thickness skin graft donor sites in 39 patients. The intervention resulted in zero bleeding complications amongst patients studied, with 64.1% reporting no pain at dressing removal and epithelialisation rates comparable to standard modalities. The authors subsequently incorporated this dressing into their standard clinical protocol based on these promising initial results.
UK applicability
The findings are potentially applicable to UK plastic and reconstructive surgery practice, as donor site management is a universal clinical challenge. However, the study's small sample size and single-centre design would warrant validation in larger, multicentre UK cohorts before widespread adoption.
Key measures
Bleeding complications (binary: present/absent); pain using Numerical Rating Scale; percentage epithelialisation assessed by clinician; donor site area (cm²); timing of dressing removal (postoperative days 4-7)
Outcomes reported
The study assessed pain levels, bleeding complications, and epithelialisation percentage in patients treated with a collagen/oxidised regenerated cellulose (C/ORC) dressing on split-thickness skin graft donor sites.
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