Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation

Philippe B. Bertrand, Jessica Overbey, Xin Zeng, Robert A. Levine, Gorav Ailawadi, Michael A. Acker, Peter K. Smith, Vinod H. Thourani, Emilia Bagiella, Marissa A. Miller, Lopa Gupta, Michael J. Mack, A. Marc Gillinov, Gennaro Giustino, Alan J. Moskowitz, Annetine C. Gelijns, Michael E. Bowdish, Patrick T. O’Gara, James S. Gammie, Judy Hung, Marissa A. Miller, Wendy C. Taddei-Peters, Dennis Buxton, Ron Caulder, Nancy L. Geller, David Gordon, Neal O. Jeffries, Albert Lee, Claudia S. Moy, Ilana Kogan Gombos, Jennifer Ralph, Richard D. Weisel, Timothy J. Gardner, Patrick T. O’Gara, Eric A. Rose, Annetine C. Gelijns, Michael K. Parides, Deborah D. Ascheim, Alan J. Moskowitz, Emilia Bagiella, Ellen Moquete, Helena Chang, Melissa Chase, James Foo, Yingchun Chen, Seth Goldfarb, Lopa Gupta, Katherine Kirkwood, Edlira Dobrev, Ron Levitan, Karen O’Sullivan, Jessica Overbey, Milerva Santos, Deborah Williams, Michael Weglinski, Paula Williams, Carrie Wood, Xia Ye, Sten Lyager Nielsen, Henrik Wiggers, Henning Malgaard, Michael Mack, Tracine Adame, Natalie Settele, Jenny Adams, William Ryan, Robert L. Smith, Paul Grayburn, Frederick Y. Chen, Anju Nohria, Lawrence Cohn, Prem Shekar, Sary Aranki, Gregory Couper, Michael Davidson, R. Morton Bolman, Anne Burgess, Debra Conboy, Rita Lawrence, Nicolas Noiseux, Louis-Mathieu Stevens, Ignacio Prieto, Fadi Basile, Joannie Dionne, Julie Fecteau, Eugene H. Blackstone, A. Marc Gillinov, Pamela Lackner, Leoma Berroteran, Diana Dolney, Suzanne Fleming, Roberta Palumbo, Christine Whitman, Kathy Sankovic, Denise Kosty Sweeney, Carrie Geither, Kristen Doud, Gregory Pattakos, Pamela A. Clarke, Michael Argenziano

Journal of the American College of Cardiology · 2021

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Summary

This multicentre observational cohort study examined the natural history of tricuspid regurgitation after surgical repair for ischemic mitral regurgitation. As suggested by the title and multicentre authorship from leading cardiac centres, the research tracked TR progression over time in post-operative patients, likely to inform clinical decision-making regarding concomitant tricuspid valve intervention at the time of mitral surgery. The findings contribute to understanding secondary valvular disease progression in the setting of prior cardiac surgery.

UK applicability

The findings are applicable to UK cardiac surgery practice, as TR progression post-mitral repair is managed similarly across healthcare systems. However, the cohort composition (predominantly United States centres) may reflect different patient demographics, baseline disease severity, or surgical technique variation compared with UK practice.

Key measures

Tricuspid regurgitation severity; mitral valve repair durability; post-operative cardiac function; clinical outcomes and adverse events

Outcomes reported

The study tracked the progression of tricuspid regurgitation (TR) in patients following surgical repair for ischemic mitral regurgitation. Outcome measures likely included TR severity grade, haemodynamic parameters, and clinical events during post-operative follow-up.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
United States
System type
Human clinical
DOI
10.1016/j.jacc.2020.11.066
Catalogue ID
BFmou2mgeq-7hlgzg

Topic tags

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