Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

SENECA study: staging endometrial cancer based on molecular classification

Enrique Chacón, Félix Boria, R Rajagopalan Lyer, Francesco Fanfani, Mario Malzoni, Petra Bretová, Ana Luzarraga Aznar, Robert Fruscio, Marcin Jędryka, Richárd Tóth, Anna Myriam Perrone, Athanasios Kakkos, Ignacio Cristóbal Quevedo, Luigi Congedo, Vanna Zanagnolo, Sergi Fernández-González, Beatriz Ferro, Fabrice Narducci, T Hovhannisyan, Elif Akşahin, L. M. Cardenas, M Reyes Oliver, Gonzalo Nozaleda, Marta Arnáez, Marcin Misiek, Annamaria Ferrero, F Pain, Janire Zarragoitia, C. Díaz, Lorenzo Ceppi, Shamsi Mehdiyev, Fernando Roldán-Rivas, Alberto Rafael Guijarro‐Campillo, Joana Amengual, Nabil Manzour, Luisa Sánchez‐Lorenzo, Jorge M. Núñez‐Córdoba, Antonio González-Martı́n, José Ángel Mínguez, Luis Chiva, cecilia darin, Rychlik Agnieszka, Ester Miralpeix, Roberto Berretta, Natalia Palasz, Duska Beric, Dimitrios Tsolakidis, Soledad Fidalgo, Richard Schwameis, S. P. Somashekhar, İbrahim Yalçın, Radovan Pilka, Çağatay Taşkıran, Despoina Myoteri, Estibaliz Iza Rodriguez, Dariusz Wydra, Sílvia Catot, Mathias K. Fehr, Frédéric Goffin, María Luisa Ramos Ibarra, Stamatios Petousis, E Moratalla Bartolomé, Mareike Bommert, Alfonso Quesada, Shamistan Aliyev, Sara Iacoponi, Inmaculada Lozano, Krzysztof Nowosielski, Ioannis Kalogiannidis, Lampe Bjourn

International Journal of Gynecological Cancer · 2024

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Summary

The SENECA study, as suggested by the title, investigates the application of molecular classification systems to endometrial cancer staging across multiple international centres. The work represents a collaborative effort to evaluate whether molecular profiling can refine or improve upon traditional staging approaches in gynaecological oncology. The specific methodology and findings cannot be confirmed without access to the full text or abstract.

UK applicability

If validated, molecular staging approaches could inform UK gynaecological oncology practice and treatment stratification in NHS cancer services, pending adoption by relevant guidelines such as those from RCOG or NICE.

Key measures

Molecular classification markers; endometrial cancer staging; clinical outcomes correlated with molecular subtypes

Outcomes reported

The study appears to evaluate molecular classification approaches for staging endometrial cancer, as suggested by the title's reference to staging based on molecular classification rather than conventional histopathological methods.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Multi-centre observational study or cohort analysis
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1136/ijgc-2024-005711
Catalogue ID
BFmowc1zyw-8utnu4

Topic tags

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