Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Phytochemical Composition and Larvicidal Activity of Sida acuta Oil Extract Against Aedes aegypti Larvae

Jefferson Rocha de A

Bioscience Biotechnology Research Communications · 2025

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Summary

This laboratory study examined the phytochemical profile and mosquito-larvicidal potential of Sida acuta leaf oil extract as an eco-friendly alternative to synthetic insecticides. Qualitative screening identified high levels of alkaloids, steroids and phenols, alongside lower concentrations of flavonoids, tannins and glycosides. Despite the presence of multiple bioactive compounds, larvicidal testing against Aedes aegypti first-instar larvae yielded low mortality rates (1–3% over 72 hours) with no significant dose–response relationship, suggesting limited practical efficacy under the tested conditions.

UK applicability

This work contributes to the global exploration of plant-based mosquito control agents, though it does not directly address UK agricultural or public health contexts. Aedes aegypti control is not a priority in the UK climate; findings may be relevant to researchers in tropical and subtropical regions seeking alternatives to synthetic insecticides.

Key measures

Qualitative and quantitative phytochemical analysis (alkaloids, steroids, phenols, flavonoids, tannins, glycosides, terpenoids, anthraquinones, saponins, cyanides, oxalates, phytates); larval mortality rate (%) at 24, 48, and 72 hours; knock-down occurrence within first hour; concentration-dependent response (12.5–125 ppb)

Outcomes reported

The study characterised the phytochemical composition of Sida acuta leaf oil extract and evaluated its larvicidal efficacy against Aedes aegypti larvae across varying concentrations (12.5–125 ppb) and collection times (morning versus evening). Mortality rates and knock-down effects were monitored over 72 hours post-exposure.

Theme
Nutrition & health
Subject
Phytochemicals & bioactive compounds
Study type
Research
Study design
Laboratory experimental study
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.21786/bbrc/18.3.3
Catalogue ID
BFmowc26qm-z2cldr

Topic tags

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