Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Synergism of phytochemicals of the plant food matrix: mechanisms, functionality

I.A. Machneva

Fruit growing and viticulture of South Russia · 2025

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Summary

This narrative review, published in a Russian horticultural and viticulture journal, surveys the literature on synergistic interactions between phytochemical compounds within the plant food matrix. It examines the mechanistic basis by which combinations of bioactive substances (BAS) can overcome the limited bioavailability that constrains the efficacy of individual phytonutrients. The paper situates synergism as a key principle in the development of functional foods and bioactive food ingredients for chronic disease prevention and immune support.

UK applicability

Although the paper is published in a Russian journal and likely draws on international literature, its findings on phytochemical synergism and bioavailability are broadly applicable to UK food science, functional food development, and dietary guidance contexts, particularly in relation to fruit and vegetable consumption and nutrient density research.

Key measures

Bioavailability and bioaccessibility of bioactive phytochemical compounds (BAS); synergistic interaction effects between phytonutrient combinations; pharmacological and functional outcomes of combined phytochemical action

Outcomes reported

The review examines combinations of phytonutrients that produce synergistic effects on bioaccessibility and bioavailability, with a focus on mechanisms by which plant food matrix components interact to enhance functional activity and chronic disease prevention.

Theme
Nutrition & health
Subject
Phytochemicals & bioactive compounds
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Food supply chain
DOI
10.30679/2219-5335-2025-3-93-127-142
Catalogue ID
NRmo3dpodv-000

Topic tags

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