Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Immobilization of Chenopodium murale-Derived Phytase on Novel Carriers: A Sustainable Approach to Enhance Nutrient Bioavailability in Cereal-Based Foods.

K. Rehman; Ehab A Abdelrahman; Mohammed Alissa; Abdullah Alghamdi; Suad A. Alghamdi; Mohammed A. Alshehri; Ghfren S Aloraini; Abdullah Albelasi; M. Abou-Krisha; Abdulrahman G. Alhamzani

Journal of Agricultural and Food Chemistry · 2025

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Summary

This study examines the immobilisation of phytase sourced from Chenopodium murale onto three carrier materials — sodium alginate/PVA beads, cellulose beads, and glass microspheres — as a means of enhancing phytic acid hydrolysis in cereal-based foods. Glass microsphere carriers, employing covalent bonding, demonstrated superior catalytic performance, stability, and reusability compared with entrapment-based matrices. The findings suggest that carrier-immobilised plant-derived phytase may offer a practical and sustainable strategy for improving mineral bioavailability in staple grain products.

UK applicability

Whilst this study was not conducted in a UK context, its findings are broadly applicable to UK food processing and cereal manufacturing sectors, where reducing phytate-bound mineral losses is relevant to addressing dietary iron, zinc, and phosphorus bioavailability in plant-based and wholegrain food products.

Key measures

Phytase activity retention (%); rate constant K (min⁻¹); half-hydrolysis time τ50 (min); full hydrolysis time τ_complete (min); phytic acid hydrolysis efficiency; enzyme reusability across cycles

Outcomes reported

The study measured phytase catalytic activity, stability, and reusability across three carrier systems, assessing phytic acid hydrolysis kinetics in cereal-based food matrices. Key performance metrics including rate constants, half-hydrolysis time, and full hydrolysis time were reported for the optimised glass microsphere carrier.

Theme
Nutrition & health
Subject
Food processing & nutrient bioavailability
Study type
Research
Study design
Laboratory experimental study
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Food supply chain
DOI
10.1021/acs.jafc.5c04881
Catalogue ID
NRmo3dpodv-00j

Topic tags

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