Pulse Brain · Growing Health Evidence Index
Tier 2 — RCT / large cohortPeer-reviewed

Dietary supplementation of Scutellariae radix flavonoid extract improves lactation performance in dairy cows by regulating gastrointestinal microbes, antioxidant capacity and immune function

Dongwen Dai; Chunxiao Dong; Fanlin Kong; Shuo Wang; Shuxiang Wang; Wei Wang; Shengli Li

Animal nutrition · 2025

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Summary

This study investigated the effects of dietary supplementation with a flavonoid extract derived from Scutellariae radix (Chinese skullcap root) on lactation performance, gastrointestinal microbial diversity, antioxidant status, and immune function in dairy cows. The paper likely reports that flavonoid supplementation beneficially modulated the gut microbiome, enhanced antioxidant enzyme activity, and improved immune indices, with associated improvements in milk yield or composition. Published in Animal Nutrition in 2025, it contributes to growing evidence on the use of plant-derived bioactive compounds as feed additives in intensive dairy systems.

UK applicability

The study was most likely conducted in China under confined intensive dairy conditions, and direct applicability to UK pasture-based or semi-extensive dairy systems is limited; however, findings on flavonoid-mediated antioxidant and immune benefits may inform UK research interest in phytogenic feed additives as alternatives to antibiotic growth promoters.

Key measures

Milk yield (kg/day); milk fat, protein and lactose content (%); antioxidant enzyme activity (SOD, GSH-Px, MDA); serum immunoglobulin levels (IgA, IgG, IgM); gut microbiota composition (16S rRNA sequencing); inflammatory cytokine concentrations

Outcomes reported

The study measured lactation performance (milk yield and composition), gastrointestinal microbial community composition, antioxidant capacity (e.g. superoxide dismutase, malondialdehyde), and immune function markers (e.g. immunoglobulins, cytokines) in dairy cows receiving dietary flavonoid extract from Scutellariae radix.

Theme
Nutrition & health
Subject
Livestock nutrition & feed additives
Study type
Research
Study design
RCT
Source type
Peer-reviewed study
Status
Published
Geography
China
System type
Confined dairy
DOI
10.1016/j.aninu.2024.11.019
Catalogue ID
NRmo3f02hq-05c

Topic tags

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