Summary
This review, published in Immunity & Ageing in 2025, synthesises current evidence on plant-derived phytochemicals with potential anti-aging effects on the skin, drawing on a body of literature spanning in vitro, in vivo, and likely some clinical studies. The authors — affiliated with Turkish research institutions with expertise in food chemistry and phytochemistry — assess how compounds such as polyphenols, terpenoids, and carotenoids may counteract key mechanisms of skin ageing, including oxidative damage, chronic low-grade inflammation, and extracellular matrix degradation. The paper likely serves as a reference framework for researchers and formulators working at the intersection of nutritional science, dermatology, and phytochemistry.
UK applicability
While not UK-specific, the findings are broadly applicable to UK nutritional health research, cosmeceutical regulation, and dietary guidance contexts; UK researchers and policymakers interested in food-derived bioactives and healthy ageing may find the mechanistic framework and compound classifications useful.
Key measures
Phytochemical classes reviewed; mechanisms of action (e.g. antioxidant activity, collagen synthesis, UV protection); skin ageing biomarkers (e.g. wrinkle formation, skin elasticity, oxidative stress markers)
Outcomes reported
The review likely examined the evidence base for plant-based phytochemicals — such as polyphenols, carotenoids, and flavonoids — in mitigating skin ageing processes, including oxidative stress, collagen degradation, and inflammation. It probably reported on both topical and dietary routes of exposure and their associated skin health outcomes.
Topic tags
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