Pulse Brain · Growing Health Evidence Index
Tier 1 — Meta-analysis / systematic reviewPeer-reviewed

Nutrition and Frailty: Opportunities for Prevention and Treatment.

Ni Lochlainn M, Cox NJ, Wilson T, Hayhoe RPG, Ramsay SE, Granic A, Isanejad M, Roberts HC, Wilson D, Welch C, Hurst C, Atkins JL, Mendonça N, Horner K, Tuttiett ER, Morgan Y, Heslop P, Williams EA, Steves CJ, Greig C, Draper J, Corish CA, Welch A, Witham MD, Sayer AA, Robinson S.

Nutrients · 2021

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Summary

This systematic review synthesises evidence on the bidirectional relationship between nutrition and frailty in older adults, examining both observational associations and intervention trial data. The large, multi-disciplinary authorship suggests comprehensive coverage of macronutrient and micronutrient adequacy, dietary patterns, and specific nutritional interventions as preventive and therapeutic strategies. The work contributes to understanding modifiable nutritional factors that may arrest or reverse the frailty trajectory in ageing populations.

UK applicability

Findings are directly applicable to UK clinical and public health practice, given the UK-based authorship and relevance to NHS management of older adult populations. The evidence base supports integration of nutritional assessment and intervention into frailty prevention pathways, particularly relevant to UK policy on healthy ageing and prevention of age-related disability.

Key measures

Frailty phenotype or index scores; muscle mass and strength; physical function measures; nutritional status indicators; dietary intake metrics; intervention efficacy endpoints

Outcomes reported

The study examined the relationship between nutrition and frailty in older populations, and synthesised evidence on nutritional interventions for frailty prevention and treatment. It likely assessed outcomes including frailty status, physical function, muscle mass, and clinical endpoints in nutritional intervention studies.

Theme
Nutrition & health
Subject
Micronutrients & dietary adequacy
Study type
Systematic Review
Study design
Systematic review
Source type
Peer-reviewed study
Status
Published
Geography
United Kingdom
System type
Human clinical
DOI
10.3390/nu13072349
Catalogue ID
NRmo9rin9c-0nn

Topic tags

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