Summary
This narrative review in Science China Life Sciences consolidates recent advances in RNA structurome research, synthesising progress across structural biology methodologies, computational approaches, and applications. Drawing on contributions from a large international author group, the paper reflects the rapid expansion of technologies enabling large-scale characterisation of RNA conformations. The review addresses both fundamental discoveries in RNA structural biology and emerging biotechnological applications of RNA structural knowledge.
UK applicability
The methodological advances in RNA structure characterisation have potential relevance to UK research institutions and biotech sectors engaged in molecular biology and synthetic biology applications, though direct relevance to agricultural or nutritional science is limited unless applied to crop or microbial biotechnology.
Key measures
RNA structural characterisation technologies, computational approaches, structural dynamics measurements, and their biological applications
Outcomes reported
The review synthesises recent technological and computational advances in characterising RNA three-dimensional structures at scale. It consolidates progress in structural biology methodologies applied to RNA and their emerging biotechnological applications.
Topic tags
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