Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Enhancing sourdough fermentation with AI and multi-omics: From natural diversity to synthetic microbial community

Yujuan Yu, Jiale Wang, Faizan Ahmed Sadiq, Honghong Cheng, Aowen Liu, Yan Liu, Senmiao Tian, Jing Liang, Ling Zhu, Guohua Zhang

Trends in Food Science & Technology · 2025

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Summary

This paper applies artificial intelligence and multi-omics profiling (genomics, metabolomics, and proteomics) to map natural microbial diversity in sourdough fermentation and rationally design synthetic microbial communities. By integrating high-dimensional omics data, the authors developed predictive models to optimise microbial consortium composition for enhanced fermentation performance. The work represents a systems-level approach to precision fermentation microbiota engineering with potential applications in bread quality and nutritional enhancement.

UK applicability

The methodology is directly applicable to UK artisanal and industrial bakery sectors, particularly for craft sourdough producers seeking to standardise fermentation and enhance nutritional value. However, applicability depends on whether findings translate to commercial-scale production and whether any regulatory approval is needed for synthetic starter cultures.

Key measures

Microbial taxonomic composition, metabolite profiles, protein expression patterns, fermentation kinetics, bread quality parameters, and putative nutritional or functional properties derived from multi-omics integration

Outcomes reported

The study characterised natural microbial diversity in sourdough starters using multi-omics (genomic, metabolomic, and proteomic) data and developed AI-informed synthetic microbial consortia to enhance fermentation performance. Likely outcomes include improved bread quality, nutritional composition, or functional properties achieved through optimised microbial community composition.

Theme
Nutrition & health
Subject
Food processing & bioavailability
Study type
Research
Study design
Laboratory / in vitro study with systems biology approach
Source type
Peer-reviewed study
Status
Published
System type
Food supply chain
DOI
10.1016/j.tifs.2025.105233
Catalogue ID
SNmobqw1qg-27ci4y

Topic tags

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