Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Factors influencing the bioactivity of natural matrices: The case of osmolarity-dependent modulation of cell viability by different dilutions of camel urines

Carlos Iglesias Pastrana, Maria Noemi Sgobba, Francisco Javier Navas González, Juan Vicente Delgado Bermejo, Ciro Leonardo Pierri, Giovanni Lentini, Biagia Musio, Taher Kamal Sayed Osman, Vito Gallo, Iola F. Duarte, Lorenzo Guerra, Elena Ciani

Research in Veterinary Science · 2024

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Summary

This in vitro study examined the bioactivity of camel urine as a natural matrix, specifically investigating how osmolarity-dependent mechanisms influence cell viability across serial dilutions. The work appears to characterise the biochemical factors within camel urine that may influence cellular responses, as suggested by the title's focus on osmolarity modulation. The findings contribute to understanding the physiological effects of traditionally-used animal-derived preparations at the cellular level.

UK applicability

Limited direct applicability to UK farming or public health policy, as the study is a mechanistic in vitro investigation rather than a field or human clinical trial. However, findings on bioactivity of animal-derived matrices may inform broader research into unconventional livestock products or traditional veterinary preparations.

Key measures

Cell viability under varying osmolarity conditions; effects of different camel urine dilutions on cell survival and proliferation

Outcomes reported

The study investigated how different dilutions of camel urine modulate cell viability in vitro, with particular attention to osmolarity-dependent mechanisms. Cell viability was measured across a range of urine dilutions to characterise bioactivity of the natural matrix.

Theme
Nutrition & health
Subject
Other / interdisciplinary
Study type
Research
Study design
Laboratory / in vitro experimental study
Source type
Peer-reviewed study
Status
Published
System type
Laboratory / in vitro
DOI
10.1016/j.rvsc.2024.105419
Catalogue ID
SNmohi6kvj-qo9h29

Topic tags

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