Pulse Brain · Growing Health Evidence Index
Tier 3 — Observational / field trialPeer-reviewed

Survival after minimally invasive surgery in early cervical cancer: is the intra-uterine manipulator to blame?

Andra Nica, Soyoun Rachel Kim, Lilian T. Gien, Allan Covens, Marcus Q. Bernardini, Geneviève Bouchard‐Fortier, Rachel Kupets, Taymaa May, Danielle Vicus, Stéphane Laframboise, Liat Hogen, Maria C. Cusimano, Sarah E. Ferguson

International Journal of Gynecological Cancer · 2020

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Summary

This retrospective cohort study, conducted across Canadian gynaecological oncology centres, evaluated whether intra-uterine manipulators used during minimally invasive hysterectomy for early cervical cancer were associated with worse survival outcomes. The research addresses emerging safety concerns about potential tumour dissemination during minimally invasive surgical approaches to early cervical cancer. The findings contribute to understanding the risk–benefit profile of instrumentation choices in gynaecological oncology.

UK applicability

The findings are directly applicable to UK gynaecological oncology practice, as surgical techniques and intra-uterine manipulator use are standardised across North American and European centres. Results may inform National Institute for Health and Care Excellence (NICE) guidance on minimally invasive approaches to early cervical cancer management.

Key measures

Survival rates, disease recurrence, and association with intra-uterine manipulator use during minimally invasive hysterectomy

Outcomes reported

The study examined survival outcomes in patients undergoing minimally invasive hysterectomy for early cervical cancer, specifically investigating whether intra-uterine manipulators were associated with adverse survival.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Research
Study design
Observational cohort
Source type
Peer-reviewed study
Status
Published
Geography
Canada
System type
Human clinical
DOI
10.1136/ijgc-2020-001816
Catalogue ID
SNmoht1vhk-jb0thr

Topic tags

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