Summary
This systematic review synthesises peer-reviewed evidence on microRNA biomarkers in lung cancer, identifying candidate miRNAs with demonstrated or proposed prognostic and predictive utility for precision medicine applications. The authors evaluated miRNA expression signatures to assess their value in stratifying patient risk and guiding personalised treatment. Whilst a significant contribution to molecular oncology literature, the work's direct relevance to farming systems, soil health, and food-based nutrition is limited; potential connections to the Vitagri Pulse catalogue would be indirect, through diet-related cancer prevention mechanisms or nutrient-gene interactions in oncology as suggested by contemporary nutritional epidemiology.
Regional applicability
The findings on miRNA biomarkers for lung cancer prognosis are applicable to UK clinical oncology and precision medicine development. However, this work does not directly address food systems, agricultural practices, or nutrition-related interventions and therefore has limited direct applicability to UK farming policy or soil health initiatives.
Key measures
MicroRNA expression signatures; prognostic and predictive utility of candidate miRNAs; patient risk stratification metrics
Outcomes reported
The study identified and synthesised evidence on microRNA expression signatures with demonstrated or proposed prognostic and predictive value in lung cancer. The review evaluated candidate miRNAs for their utility in patient risk stratification and informing personalised treatment strategies.
Topic tags
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