Summary
This comprehensive narrative review synthesises current knowledge on mycotoxin contamination of food and feed, examining the fungal ecology, global regulatory frameworks, and health consequences of exposure. The authors evaluate molecular mechanisms of mycotoxin toxicity alongside recent technological innovations in detection and identification, whilst identifying a significant gap: despite numerous laboratory-scale innovations, no single commercialised device currently detects all naturally occurring mycotoxins. The review links emerging mitigation strategies to the molecular pathways activated upon exposure.
UK applicability
UK food and feed safety regulations are aligned with European Union frameworks for mycotoxin limits, which the paper addresses as part of global regulatory review. The findings on detection innovations and mitigation strategies may inform UK industry and regulatory body efforts to reduce mycotoxin-related food safety incidents, though UK-specific case studies are not identified in the abstract.
Key measures
Regulatory mycotoxin limits by country; molecular and signaling pathways activated by mycotoxin exposure; genotoxic and cytotoxic effects; detection device specifications and performance characteristics
Outcomes reported
The review examined geographical regulatory guidelines for mycotoxin control, molecular signaling pathways and toxicity mechanisms in humans and animals, recent developments in sensitive detection and identification methods, and advancements in mitigating health consequences from mycotoxin exposure.
Topic tags
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