Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

STaRT-RWE: structured template for planning and reporting on the implementation of real world evidence studies

Shirley Wang, Simone Pinheiro, Hua Wei, Peter Arlett, Yoshiaki Uyama, Jesse A. Berlin, Dorothee B. Bartels, Kristijan H. Kahler, Lily G. Bessette, Sebastian Schneeweiß

BMJ · 2021

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Summary

STaRT-RWE is a structured template developed to standardise the planning and reporting of real-world evidence studies. The template addresses a recognised gap in methodological guidance for RWE implementation across diverse settings. This work supports transparency, reproducibility, and comparability of real-world evidence research by providing a comprehensive framework for study design and reporting.

UK applicability

This methodology template is directly applicable to UK health research and regulatory contexts, particularly for studies informing medicines safety and efficacy decisions by regulatory bodies such as the MHRA and NHS implementation research.

Key measures

Template components for RWE study planning and implementation reporting; standardisation of RWE study design elements

Outcomes reported

The paper presents STaRT-RWE, a structured template for planning and reporting the implementation of real-world evidence (RWE) studies. It provides guidance on standardising the design, conduct, and reporting of RWE studies across diverse healthcare and research contexts.

Theme
Measurement & metrics
Subject
Measurement methods & nutrient profiling
Study type
Guideline
Study design
Methodology/guideline development
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Other
DOI
10.1136/bmj.m4856
Catalogue ID
SNmoixnvw4-yejnml

Topic tags

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