Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia

Lars Bendtsen, Joanna M. Zakrzewska, Tone Bruvik Heinskou, Mojgan Hodaie, Paulo Roberto Lacerda Leal, Turo Nurmikko, Mark Obermann, G. Cruccu, Stine Maarbjerg

The Lancet Neurology · 2020

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Summary

This Lancet Neurology review synthesises current understanding of trigeminal neuralgia, encompassing diagnostic techniques, aetiological classification, underlying pathophysiology, and contemporary management approaches. The authors, a multinational panel of neurology specialists, present advances in both pharmacological and interventional therapies as they were understood in 2020. The paper appears intended as a clinical reference for diagnosis and evidence-based treatment selection in primary and specialist care.

UK applicability

As a clinical review of trigeminal neuralgia management, findings are applicable to UK neurology and general practice, where diagnostic and treatment protocols align with international standards. However, this paper falls outside Vitagri's core remit of farming systems, soil health, nutrient density, and food system contributions to human health.

Key measures

Clinical diagnostic criteria, neuroimaging findings, pain severity and classification, treatment efficacy and safety outcomes

Outcomes reported

The study reviewed advances in diagnostic approaches, classification systems, pathophysiological mechanisms, and therapeutic management strategies for trigeminal neuralgia. It synthesised current evidence on pharmacological, surgical, and interventional treatments for this chronic pain condition.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
System type
Human clinical
DOI
10.1016/s1474-4422(20)30233-7
Catalogue ID
SNmoj7nqf5-gizm1o

Topic tags

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