Pulse Brain · Growing Health Evidence Index
Tier 4 — Narrative / commentaryPeer-reviewed

IMI 2021 Yearly Digest

Monica Jong, Jost B. Jonas, James S. Wolffsohn, David A. Berntsen, Pauline Cho, Danielle Clarkson-Townsend, Daniel Ian Flitcroft, Kate Gifford, Annechien E. G. Haarman, Machelle T. Pardue, Kathryn Richdale, Padmaja Sankaridurg, Milly S. Tedja, Christine F. Wildsoet, Joan E. Bailey‐Wilson, Jeremy A. Guggenheim, Christopher J. Hammond, Jaakko Kaprio, Stuart MacGregor, David A. Mackey, Anthony M. Musolf, Caroline C. W. Klaver, Virginie J. M. Verhoeven, Véronique Vitart, Earl L. Smith

Investigative Ophthalmology & Visual Science · 2021

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Summary

This International Myopia Institute Yearly Digest provides a comprehensive narrative review of myopia research published between 2019 and mid-2020. The review synthesises advances across definitions (including premyopia and pathologic myopia), genetics (identifying 336 new genetic loci), novel interventions (low-dose atropine, orthokeratology, defocus-incorporated spectacles, latanoprost), and clinical management standards. The authors highlight emerging ethical dilemmas in placebo-controlled trials, methodological considerations in reporting myopia reduction metrics, and tensions between myopia prevention and quality-of-life outcomes.

UK applicability

The clinical management recommendations and intervention evidence base reviewed here are applicable to UK optometric and ophthalmological practice, particularly regarding adoption of myopia control strategies in paediatric populations. However, the digest does not address country-specific prevalence, healthcare delivery models, or reimbursement policies relevant to the UK NHS.

Key measures

Publication volume (n=1,000 articles); number of genetic loci identified (336 new loci); categories of advancement (definitions, experimental models, genetics, interventions, clinical trials, clinical management)

Outcomes reported

A systematic review of over 1,000 peer-reviewed articles on myopia published between 2019 and mid-2020, identifying key advances in definitions, genetic loci, pharmacological and optical interventions, and clinical management strategies. The digest synthesises emerging evidence on myopia prevention and control treatments and highlights evolving ethical and methodological considerations in myopia research.

Theme
General food systems / other
Subject
Other / interdisciplinary
Study type
Narrative Review
Study design
Narrative review
Source type
Peer-reviewed study
Status
Published
Geography
International
System type
Human clinical
DOI
10.1167/iovs.62.5.7
Catalogue ID
SNmojad09m-y1jcy8

Topic tags

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